Prognostic Value of Contrast-Enhanced Magnetic Resonance Imaging in Brainstem Gliomas
| Autor: | Robert D. Tien, Albert Moghrabi, Tracy Kerby, Henry S. Friedman |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Gadolinium DTPA
Male Pathology medicine.medical_specialty Adolescent Central nervous system Contrast Media Classification scheme Central nervous system disease Organometallic Compounds medicine Brainstem glioma Humans Neoplasm Invasiveness Child Survival rate Contrast-enhanced Magnetic Resonance Imaging medicine.diagnostic_test Brain Neoplasms business.industry Infant Magnetic resonance imaging Glioma General Medicine Pentetic Acid Prognosis medicine.disease Magnetic Resonance Imaging Survival Rate medicine.anatomical_structure Child Preschool Pediatrics Perinatology and Child Health Female Surgery Neurology (clinical) Brainstem business Brain Stem |
| Zdroj: | Pediatric Neurosurgery. 23:293-298 |
| ISSN: | 1423-0305 1016-2291 |
| Popis: | Brainstem gliomas are an important oncologic problem in the pediatric age group, constituting between 10 and 15% of childhood central nervous system neoplasms. A new classification scheme based on magnetic resonance imaging (MRI) has recently been proposed leading to speculation that gadolinium-DTPA-enhanced MRI may prove useful in defining the prognosis of subsets of patients with these tumors. We retrospectively reviewed gadolinium-DTPA-enhanced MRIs in 26 consecutive newly diagnosed pediatric patients (11 males, 15 females) from our institution between June 1988 and June 1994 with the diagnosis of diffuse brainstem glioma. The site, extent of invasion, T1 and T2 signals, and the pattern and the degree of contrast enhancement of the tumors were evaluated. We correlated the image features, clinical symptoms, and survival period in each patient. Seventeen tumors demonstrated contrast enhancement and 9 did not. The survival in the whole group ranged between 3 months and5 years with a median of 9 months. There was no statistical difference in the median survival between patients with or without contrast enhancement (11 versus 8 months). |
| Databáze: | OpenAIRE |
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