Development of a QuEChERS-Based Method for Determination of Carcinogenic 2-Nitrofluorene and 1-Nitropyrene in Rice Grains and Vegetables: A Comparative Study with Benzo[a]pyrene
| Autor: | Wan Chan, Kailin Deng |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Food Contamination
010501 environmental sciences Quechers 01 natural sciences chemistry.chemical_compound Vegetables Benzo(a)pyrene polycyclic compounds Chromatography High Pressure Liquid Carcinogen 0105 earth and related environmental sciences Fluorenes Pyrenes 010401 analytical chemistry Oryza General Chemistry 0104 chemical sciences chemistry 1-Nitropyrene Environmental chemistry Seeds Carcinogens Hong Kong Pyrene Environmental Pollutants Polycyclic Hydrocarbons 2-Nitrofluorene General Agricultural and Biological Sciences Food contaminant |
| Zdroj: | Journal of Agricultural and Food Chemistry. 65:1992-1999 |
| ISSN: | 1520-5118 0021-8561 |
| DOI: | 10.1021/acs.jafc.7b00051 |
| Popis: | Nitrated polycyclic aromatic hydrocarbons (nitro-PAHs) are ubiquitous environmental pollutants attracting increasing attention because of their potent mutagenicity to humans. Previous studies of nitro-PAHs focused on investigating their formation mechanisms and detecting them in atmospheric environment; however, few studies have reported their occurrence in food samples, and regulations on nitro-PAHs are still lacking. We report in this study the development and application of a quick, easy, cheap, effective, rugged, and safe (QuEChERS) method for determination of nitro-PAHs in rice and vegetable samples. Analysis of the collected samples by the validated method revealed 1-nitropyrene and 2-nitrofluorene were widespread food contaminants. A comparative study with benzo[a]pyrene, the commonly used marker for PAH exposure, showed that carcinogenic nitro-PAHs existed in rice and vegetables at similar concentrations. Dietary exposure risk, which was estimated based on the surveillance data, suggested 3.28-5.03 ng/kg/day of nitro-PAHs exposure for Hong Kong citizens from rice grains and vegetables. |
| Databáze: | OpenAIRE |
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