Impressive predictive value of ankle-brachial index for very long-term outcomes in patients with cardiovascular disease: IMPACT-ABI study

Autor: Wataru Shoin, Jun Koyama, Hitoshi Nishimura, Yasushi Ueki, Koichiro Kuwahara, Koji Yoshie, Naoyuki Abe, Yasutaka Oguchi, Tatsuya Saigusa, Uichi Ikeda, Masatoshi Minamisawa, Hirohiko Motoki, Soichiro Ebisawa, Takashi Miura, Naoto Hashizume, Mikiko Harada, Tomoaki Mochidome
Rok vydání: 2017
Předmět:
Male
Myocardial Infarction
lcsh:Medicine
Blood Pressure
030204 cardiovascular system & hematology
Pathology and Laboratory Medicine
Antiplatelet Therapy
Vascular Medicine
0302 clinical medicine
Endocrinology
Risk Factors
Medicine and Health Sciences
030212 general & internal medicine
Myocardial infarction
lcsh:Science
Stroke
Aged
80 and over
Multidisciplinary
Pharmaceutics
Hazard ratio
Middle Aged
Hospitalization
Cardiovascular Diseases
Nephrology
Predictive value of tests
Cardiology
cardiovascular system
Female
Research Article
medicine.medical_specialty
Endocrine Disorders
Hemorrhage
03 medical and health sciences
Signs and Symptoms
Drug Therapy
Predictive Value of Tests
Diagnostic Medicine
Internal medicine
Diabetes mellitus
Medical Dialysis
medicine
Diabetes Mellitus
Humans
Ankle Brachial Index
cardiovascular diseases
Aged
Retrospective Studies
Heart Failure
business.industry
lcsh:R
Retrospective cohort study
medicine.disease
Surgery
body regions
Heart failure
Metabolic Disorders
lcsh:Q
business
human activities
Mace
Zdroj: PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0177609 (2017)
ISSN: 1932-6203
Popis: Background The ankle—brachial index (ABI) is a marker of generalized atherosclerosis and is predictive of future cardiovascular events. However, few studies have assessed its relation to long-term future cardiovascular events, especially in patients with borderline ABI. We therefore evaluated the relationship between long-term future cardiovascular events and ABI. Methods In the IMPACT-ABI study, a single-center, retrospective cohort study, we enrolled 3131 consecutive patients (67 ± 13 years; 82% male) hospitalized for cardiovascular disease and measured ABI between January 2005 and December 2012. After excluding patients with an ABI > 1.4, the remaining 3056 patients were categorized as having low ABI (≤ 0.9), borderline ABI (0.91–0.99), or normal ABI (1.00–1.40). The primary endpoint was MACE (cardiovascular death, myocardial infarction [MI] and stroke). The secondary endpoints were cardiovascular death, MI, stroke, admission due to heart failure, and major bleeding. Results During a 4.8-year mean follow-up period, the incidences of MACE (low vs. borderline vs. normal: 32.9% vs. 25.0% vs. 14.6%, P
Databáze: OpenAIRE
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