Consistency of isochromosome 7q and trisomy 8 in hepatosplenic gammadelta T-cell lymphoma: detection by fluorescence In situ hybridization of a splenic touch-preparation from a pediatric patient

Autor:	Susan Coventry, Maria Koehler, Danielle Casher, Michael J. Borowitz, Ewa Z. Tomczak, Jean Pierre De Chadarévian, Hope H. Punnett, Constance A. Griffin
Rok vydání:	1999
Předmět:	Male Pathology medicine.medical_specialty T cell Spleen Aggressive lymphoma Trisomy In situ hybridization Trisomy 8 Lymphoma T-Cell Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine medicine T-cell lymphoma Humans Child In Situ Hybridization Fluorescence 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Splenic Neoplasms Liver Neoplasms Receptors Antigen T-Cell gamma-delta General Medicine medicine.disease Flow Cytometry Lymphoma Isochromosomes medicine.anatomical_structure 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health business Chromosomes Human Pair 7 Fluorescence in situ hybridization Chromosomes Human Pair 8
Zdroj:	Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 2(5)
ISSN:	1093-5266
Popis:	Hepatosplenic gamma-delta (γδ) T-cell lymphoma is a rare but increasingly recognized lymphoid malignancy predominantly affecting young adult males. It is not well appreciated in the pediatric population. We report the third case of this aggressive lymphoma in a child as well as additional support for the consistency of the recently discovered cytogenetic abnormalities, isochromosome 7q and trisomy 8, which in this case were documented using fluorescence in situ hybridization (FISH) of a touch-preparation of the spleen.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7272d797cbf13a0dd0141ff2177dcd https://pubmed.ncbi.nlm.nih.gov/10441626 Zobrazit plný text záznamu Full text from SpringerLink