Serum lipid management in patients with type 1 and type 2 diabetes: a hospital-based cohort study
| Autor: | Moritoshi Kurita, Junko Oya, Arata Ito, Yukiko Hasegawa, Chisato Isago, Tomoko Nakagami, Junnosuke Miura, Reika Tsuzura, Naoki Hirota, Yasuko Uchigata, Yuki Tanaka |
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| Rok vydání: | 2018 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases Endocrinology Diabetes and Metabolism Blood lipids 030209 endocrinology & metabolism Type 2 diabetes 030204 cardiovascular system & hematology Logistic regression 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Diabetes mellitus Internal Medicine Medicine Triglyceride business.industry nutritional and metabolic diseases medicine.disease chemistry Original Article lipids (amino acids peptides and proteins) Glycated hemoglobin business Body mass index Cohort study |
| Zdroj: | Diabetology International. 10:67-76 |
| ISSN: | 2190-1686 2190-1678 |
| DOI: | 10.1007/s13340-018-0365-z |
| Popis: | INTRODUCTION: Serum lipid management is important for patients with diabetes; however, it has not been examined in our specialized diabetes clinic. AIMS: The aim of the study was to assess the percentage of patients who did not achieve management targets (MT) for low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C) and triglycerides (TG), and explore factors related to failure to achieve lipid MT in Japanese patients with type 1 (T1D) and type 2 diabetes (T2D). METHODS: This cross-sectional study included 795 patients (35% men) with T1D and 4018 patients (60% men) with T2D attending our diabetes center. MTs for serum lipids were in accordance with the guidelines of the Japan Atherosclerosis Society. Logistic regression analysis was performed to identify factors related to failure to achieve MTs for serum lipids. RESULTS: The percentages of men/women who did not achieve MT for LDL-C were 34.1/31.8% in T1D and 40.5/52.7% in T2D. The corresponding values for TG were 35.1/14.0% in T1D and 50.1/47.9% in T2D, and for HDL-C were 2.5/0% in T1D and 8.6/2.9% in T2D. Increase in body mass index (BMI) and glycated hemoglobin (HbA1c) were significantly and independently associated with failure to achieve lipid MT in patients with T1D and T2D for both sexes. CONCLUSIONS: The percentages of our patients who did not achieve serum lipid MT were relatively high in T1D and T2D, and higher HbA1c and BMI were associated with failure to achieve serum lipid MTs. More attention should be paid to lipid management in patients with diabetes especially who have higher HbA1c and BMI in our facility. |
| Databáze: | OpenAIRE |
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