Carbimazole-induced acute cholestatic hepatitis

Autor: J. Hemet, G. Ozenne, E Bercoff, J. Doucet, Schrub Jc, N D Manchon
Rok vydání: 1989
Předmět:
Zdroj: Journal of clinical gastroenterology. 11(1)
ISSN: 0192-0790
Popis: A case of carbimazole-induced cholestatic hepatitis is presented. A woman received carbimazole for hyperthyroidism for 3 months. Five months later, she had prompt recurrence of cholestasis parameters after rechallenge (2 days of treatment). Histologic examination showed predominantly centrilobular cholestasis. Only 5 other cases have been published in the literature. An idiosyncratic mechanism seems likely.
Databáze: OpenAIRE