Immunomodulatory effects of arabinogalactan-proteins from Baptisia and Echinacea
| Autor: | Maren Wack, C. Bodinet, Birgit Classen, Wolfgang Blaschek, S. Thude |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Pharmaceutical Science
Stimulation Plant Roots Echinacea Microbiology Mice Echinacea (animal) Mucoproteins Arabinogalactan Macrophages Alveolar Drug Discovery Animals Lymphocytes Cells Cultured Nitrites Echinacea pallida Cell Proliferation Plant Proteins Arabinogalactan protein Pharmacology biology Interleukin-6 Fabaceae biology.organism_classification In vitro Immunoglobulin M Complementary and alternative medicine Cell culture Molecular Medicine Baptisia |
| Zdroj: | Phytomedicine. 13:688-694 |
| ISSN: | 0944-7113 |
| DOI: | 10.1016/j.phymed.2005.10.004 |
| Popis: | The influences of different arabinogalactan-proteins (AGPs) on proliferation and IgM-production of mouse lymphocytes as well as nitrite- and IL6-production of mouse macrophages were investigated in vitro. AGPs have been isolated and purified from roots of Baptisia tinctoria and Echinacea pallida and suspension culture of Echinacea purpurea. Comparing the AGPs, there are differences with regard to fine structure as well as to activities. AGPs from roots of B. tinctoria and E. pallida show high activity in all test systems. AGP from cell culture of E. purpurea shows no influence on proliferation of mouse lymphocytes, only weak influence on the IgM-production of mouse lymphocytes and weak stimulation of nitrite- and IL6-production in alveolar mouse macrophage culture. |
| Databáze: | OpenAIRE |
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