Antimicrobial activity of new 4,6-disubstituted pyrimidine, pyrazoline, and pyran derivatives
| Autor: | Adel A.-H. Abdel-Rahman, Asmaa I. El-Tantawy, Mahmoud M. M. Ramiz, Wael A. El-Sayed |
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| Rok vydání: | 2010 |
| Předmět: |
Pyrimidine
Stereochemistry Pharmacology toxicology Quantitative Structure-Activity Relationship Pyrazoline Microbial Sensitivity Tests medicine.disease_cause chemistry.chemical_compound Chalcones Anti-Infective Agents Drug Discovery medicine Organic chemistry Chalcone derivative Pyrans Dose-Response Relationship Drug Chemistry Pseudomonas aeruginosa Organic Chemistry Antimicrobial Streptomyces species Pyrimidines Models Chemical Pyran Pyrazoles Molecular Medicine |
| Zdroj: | Archives of Pharmacal Research. 33:647-654 |
| ISSN: | 1976-3786 0253-6269 |
| Popis: | A number of new 2,6-didisubstituted pyrimidine, pyrazoline, and pyran derivatives were synthesized starting from their chalcone derivative. The synthesized compounds displayed different degrees of antimicrobial activity against Bscillus subtilis (Gram-positive), Pseudomonas aeruginosa (Gram-negative), and Streptomyces species (Actinomycetes). |
| Databáze: | OpenAIRE |
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