Odor perception in patients with mood disorders

Autor: Emannuel Haffen, Sylvie Nezelof, Pierre Vandel, Jean-Louis Millot, Sandrine Lombion-Pouthier
Přispěvatelé: Laboratoire de Neurosciences Intégratives et Cliniques - UFC ( NEURO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Laboratoire de Neurosciences Intégratives et Cliniques - UFC (EA 481) (NEURO), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)
Jazyk: angličtina
Rok vydání: 2006
Předmět:
Male
MESH: Mood Disorders
Anorexia Nervosa
Signal Detection
Psychological

MESH: Depressive Disorder
Individuality
MESH : Aged
Audiology
MESH : Olfaction Disorders
Olfaction Disorders
0302 clinical medicine
Discrimination
Psychological

Reference Values
MESH: Olfaction Disorders
MESH: Discrimination (Psychology)
MESH : Female
MESH: Individuality
media_common
MESH : Signal Detection
Psychological

MESH: Aged
MESH: Middle Aged
MESH : Individuality
MESH: Reference Values
Cognition
MESH: Affect
Olfactory Pathways
Middle Aged
MESH : Adult
Psychiatry and Mental health
Clinical Psychology
Alcoholism
Anorexia nervosa (differential diagnoses)
Sensory Thresholds
MESH: Substance-Related Disorders
MESH : Anorexia Nervosa
Female
[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
Psychology
MESH : Mood Disorders
MESH: Anorexia Nervosa
Adult
MESH : Substance-Related Disorders
medicine.medical_specialty
Adolescent
Substance-Related Disorders
media_common.quotation_subject
MESH : Male
Olfaction
MESH : Reference Values
03 medical and health sciences
MESH: Alcoholism
Perception
MESH : Adolescent
medicine
Humans
MESH : Middle Aged
Psychiatry
Aged
MESH: Adolescent
Depressive Disorder
MESH: Humans
MESH : Olfactory Pathways
MESH : Alcoholism
Mood Disorders
Addiction
MESH : Humans
MESH: Adult
medicine.disease
MESH: Signal Detection
Psychological

MESH : Affect
MESH : Discrimination (Psychology)
MESH: Male
MESH : Depressive Disorder
030227 psychiatry
Affect
Mood
Mood disorders
Odor
[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
MESH: Sensory Thresholds
MESH: Female
030217 neurology & neurosurgery
MESH: Olfactory Pathways
MESH : Sensory Thresholds
Zdroj: Journal of Affective Disorders
Journal of Affective Disorders, Elsevier, 2006, 90 (2-3), pp.187-91. 〈10.1016/j.jad.2005.11.012〉
Journal of Affective Disorders, Elsevier, 2006, 90 (2-3), pp.187-91. ⟨10.1016/j.jad.2005.11.012⟩
ISSN: 0165-0327
DOI: 10.1016/j.jad.2005.11.012〉
Popis: Backgrounds Olfaction has obvious correlates with emotional processes but little is known about the several aspects of olfaction in psychiatric disorders characterized by mood disturbance. This research aims at pointing out the specificities of olfactory perception in patients in order to identify the specific cerebral impairments involved in these disorders. Methods Olfactory sensitivity, detection, identification, self-evaluation of intensity and pleasantness have been recorded in a control group of healthy subjects ( N = 58) and in three sample populations admitted to a Psychiatry Department: depressive patients ( N = 49), anorectic patients ( N = 17), and patients suffering from addiction to alcohol or drugs ( N = 21). Results Depressive patients have a poor sensitivity, poor detection abilities but over-evaluate the pleasantness of odors. Anorectic patients have a high sensitivity, over-evaluate the intensities of the odors but under-evaluate their pleasantness. Alcoholic/drug addicted patients showed impairments in identification. Limitation This study does not identify inter-individual differences in olfactory perception. Conclusion The psychiatric diseases, here at hand although every one of them may be characterized by depressive components, show diverging impairments in olfactory perception. When variations in sensitivity are usually attributed to peripheral cues, impairments in emotional and cognitive aspects of olfaction are typically related to specific brain structures and processes which could be particularly involved in these diseases.
Databáze: OpenAIRE