FISH Probes for Mouse Chromosome Identification

Autor:	Daniel Pinkel, Joe W. Gray, Douglas Hanahan, Paul Gold, Eric S. Lander, Yu Ping Shi, Gayatry Mohapatra, Joyce C. Miller
Rok vydání:	1997
Předmět:	Genetics Polymorphism Genetic Chromosome Mapping Biology Molecular biology Chromosome 17 (human) Mice Chromosome 16 Chromosome 3 Chromosome 18 Chromosome 19 Chromosome regions Animals Cloning Molecular DNA Probes Chromosome 21 Chromosome 22 In Situ Hybridization Fluorescence
Zdroj:	Genomics. 45:42-47
ISSN:	0888-7543
Popis:	P1 clones near the telomeres and centromeres of each mouse chromosome except Y have been selected from a mouse genomic library and mapped using fluorescence in situ hybridization (FISH). Each clone was selected to contain a genetically mapped polymorphic DNA sequence as close as possible to the centromere or telomere of a chromosome. The genetic distance from the various P1 clones to the most distal genetically mapped polymorphic sequence ranged from 0 for about half of the clones to 6.7 cM for the probe at the telomere of chromosome 14. The average distance to the most distal or proximal chromosome marker was 1.5 cM. The use of FISH with these probes for mouse chromosome identification during comparative genomic hybridization is illustrated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4f17bb78b5f5440ecf2f0e0c8dc43b https://doi.org/10.1006/geno.1997.4904 Zobrazit plný text záznamu Full Text from ScienceDirect