Antioxidant activities of peptoid-grafted chitosan films

Autor: Olivier Roy, S. Badel, Pierre-Henri Elchinger, Claude Taillefumier, Thierry Bernardi, Philippe Michaud, Sophie Faure, Cédric Delattre
Přispěvatelé: Institut de Chimie de Clermont-Ferrand (ICCF), SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Institut Pascal (IP), SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), BioFilm Control, Biopôle Clermont Limagne, Saint-Beauzire, SIGMA Clermont (SIGMA Clermont)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Applied Biochemistry and Biotechnology
Applied Biochemistry and Biotechnology, 2017, 181, pp.283-293. ⟨10.1007/s12010-016-2212-7⟩
Applied Biochemistry and Biotechnology, Humana Press, 2017, 181, pp.283-293. ⟨10.1007/s12010-016-2212-7⟩
ISSN: 0273-2289
DOI: 10.1007/s12010-016-2212-7⟩
Popis: International audience; The aim of this study was to investigate the possibility of immobilizing peptoid on chitosan film in order to generate new active material. Chitosan films have been grafted for the first time with short-length peptoid oligomers displaying antioxidant activities. The antioxidant activity of the selected peptoids was initially investigated with the DPPH assay and hydroxyl radical procedure. The metal chelating capacity of peptoids was also evaluated prior to their covalent attachment to chitosan. The benefit of chitosan functionalization with respect to its intrinsic antioxidant properties was finally evaluated in the present study. Interestingly, an increase of up to 90 % of the antioxidant activity of chitosan was observed.
Databáze: OpenAIRE