Autor: |
Yun-Yuan Tian, Yang Liu, Peng-Cheng Qiu, Yao Li, Jin-Ming Hu, Tian-Yi Li, Wen-Wen Chen, Hai-Feng Tang, Yun-Yang Lu |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Bioorganic Chemistry. 131:106305 |
ISSN: |
0045-2068 |
DOI: |
10.1016/j.bioorg.2022.106305 |
Popis: |
Phytochemical investigation on the rhizomes of Paris fargesii var. petiolata (Baker ex C. H. Wright) Wang et Tang led to the isolation of five previously undescribed steroidal saponins, parpetiosides A-E (1-5), and six known analogs (6-11). Their structures were established by extensive spectroscopic data analysis and chemical methods. Compound 5 was a rare steroidal saponin with disaccharide moiety linked at C-26 of dehydrokryptogenin that was hardly seen in the genus Paris. The cytotoxicities of the isolated compounds against three human cancer cell lines (U87, HepG2 and SGC-7901) were evaluated, and compound 1 displayed certain inhibitory effect with IC |
Databáze: |
OpenAIRE |
Externí odkaz: |
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