Protein-based fluorescent metal nanoclusters for small molecular drug screening

Autor:	Siu Yee New, Yen Nee Tan, Xiaodi Su, Yong Yu, Jianping Xie
Rok vydání:	2014
Předmět:	Drug media_common.quotation_subject Drug Evaluation Preclinical Ibuprofen Nanotechnology Catalysis Nanoclusters Metal Sulfanilamide Sulfanilamides Materials Chemistry medicine Screening method Serum Albumin Fluorescent Dyes media_common Chemistry Metals and Alloys General Chemistry Fluorescence Combinatorial chemistry Nanostructures Surfaces Coatings and Films Electronic Optical and Magnetic Materials Phenytoin visual_art Ceramics and Composites visual_art.visual_art_medium Gold Warfarin medicine.drug
Zdroj:	Chem. Commun.. 50:13805-13808
ISSN:	1364-548X 1359-7345
Popis:	A facile drug screening method based on synthesis of fluorescent gold nanoclusters inside albumin proteins loaded with small molecular drugs and comparing the relative fluorescence intensities of the resultant gold nanoclusters has been developed and successfully applied for the quantitative measurement of drug-protein binding constants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab40f5b00bc4912b1fad3e5219273f4c https://doi.org/10.1039/c4cc06914e Zobrazit plný text záznamu