Pregnancy outcome predictors in antiphospholipid syndrome: A systematic review and meta-analysis
| Autor: | Katharina Wilhelmina Maria Bloemenkamp, Maarten Limper, Anne Titia Lely, Mirthe Jasmijn Klein Haneveld, Isabel Johanna Walter, Judith Kooiman |
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| Rok vydání: | 2021 |
| Předmět: |
Lupus anticoagulant
medicine.medical_specialty Pregnancy Obstetrics business.industry Immunology Infant Newborn Pregnancy Outcome Odds ratio medicine.disease Antiphospholipid Syndrome Preeclampsia Pre-Eclampsia Antiphospholipid syndrome Meta-analysis Lupus Coagulation Inhibitor medicine Immunology and Allergy Small for gestational age Humans Premature Birth Female Live birth business |
| Zdroj: | Autoimmunity reviews. 20(10) |
| ISSN: | 1873-0183 |
| Popis: | OBJECTIVE To identify and assess the magnitude of effect of pregnancy outcome predictors in women with antiphospholipid syndrome (APS) by means of systematic review and meta-analysis. METHODS PubMed and Embase were searched (13th June 2020) for studies reporting on pre-pregnancy risk factors of pregnancy outcomes in APS patients. Literature screening and data extraction were conducted by two reviewers independently, in a blinded standardized manner. Pooled univariate odds ratios (OR) were computed using a random effects model. Heterogeneity was assessed by I2%. RESULTS The search yielded 3013 unique results; 27 records were included in this meta-analysis. Previous thrombosis was associated with a decreased live birth risk (OR 0.60, p |
| Databáze: | OpenAIRE |
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