Effect of Bombesin on Gastric Secretion and Motility in the Cat
| Autor: | Y. Minaire, M.L. Gelin, Jean-Alain Chayvialle, M. Vagne, T.J. McDonald |
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| Rok vydání: | 1982 |
| Předmět: |
Male
medicine.medical_specialty Motility complex mixtures digestive system Gastric Acid chemistry.chemical_compound fluids and secretions Pepsin Internal medicine Gastrins Pyloric Antrum medicine Animals Insulin Secretion Gastric Juice CATS biology digestive oral and skin physiology Gastroenterology Bombesin Pepsin A Gastric secretion Pentagastrin Endocrinology chemistry Antral motility Cats biology.protein Female Gastrointestinal Motility Peptides hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Digestion. 24:5-13 |
| ISSN: | 1421-9867 0012-2823 |
| DOI: | 10.1159/000198768 |
| Popis: | The effect of bombesin on acid and pepsin secretion and antral motility was compared to that of pentagastrin in conscious cats. Bombesin stimulated acid secretion to 65% of the maximal response to pentagastrin but induced a stronger pepsin secretion than any dose of pentagastrin. As to antral motility, bombesin first induced an effect comparable to that of pentagastrin, with an increase of low-amplitude and a decrease of high-amplitude contractions. After about 30 min of continuous infusion, the effect of bombesin changed with a return to basal frequency for the low-amplitude contractions and an increase of high-amplitude contractions. This effect was not observed with pentagastrin nor cholecystokinin and was not explained by the variations of plasma insulin concentration. |
| Databáze: | OpenAIRE |
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