Repeated Full-Face Aesthetic Combination Treatment With AbobotulinumtoxinA, Hyaluronic Acid Filler, and Skin-Boosting Hyaluronic Acid After Monotherapy With AbobotulinumtoxinA or Hyaluronic Acid Filler
| Autor: | Hugues Cartier, Per Bergentz, Maria Norberg, Carolina Edwartz, Per Hedén, Cecilia Skoglund, Henry Delmar, Philippe Kestemont |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Esthetics Acetylcholine Release Inhibitors Dentistry Cosmetic Techniques Dermatology law.invention 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Combined treatment Patient satisfaction Randomized controlled trial law Dermal Fillers ABO blood group system Hyaluronic acid Humans Rejuvenation Medicine Botulinum Toxins Type A Hyaluronic Acid Adverse effect Wrinkle business.industry General Medicine Middle Aged Glabella Combined Modality Therapy Skin Aging Treatment Outcome medicine.anatomical_structure chemistry Patient Satisfaction Face 030220 oncology & carcinogenesis Retreatment Female Original Article Surgery medicine.symptom business |
| Zdroj: | Dermatologic Surgery |
| ISSN: | 1524-4725 1076-0512 |
| DOI: | 10.1097/dss.0000000000002165 |
| Popis: | Background Full-face aesthetic treatment involving several treatment modalities may improve facial aesthetic outcome. Objective To evaluate clinical outcomes and patient perceptions of monotherapy with either abobotulinumtoxinA (ABO) or hyaluronic acid (HA) filler followed by full-face combination treatments of ABO, HA filler, and skin-boosting HA (RSB). Materials and methods Subjects aged 35 to 50 years were randomized to monotherapy with 50 s.U ABO in the glabella or ≤1 mL HA filler in the nasolabial folds (NLFs)/cheeks. At Month 6 and Month 12, all subjects received combination treatment with ≤50 s.U ABO in the glabella, ≤2 mL HA filler in the NLFs/cheeks (and other facial areas as applicable), and ≤1 mL RSB (additional RSB treatment at Month 7). Assessments included global facial aesthetic appearance and improvement, first impression, perceived age, wrinkle severity, satisfaction questionnaires, and adverse events. Results Repeated full-face combination treatment with ABO, HA filler, and RSB was associated with considerably higher levels of aesthetic improvement and subject satisfaction than monotherapy with ABO or HA filler. Improvement rate of glabellar lines was increasing with each treatment. Conclusion Repeated combination treatment achieved greater change in global facial aesthetic appearance than monotherapy. Aesthetic improvement and subject satisfaction was high and increased with each treatment. All treatments were well tolerated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|