Treatment selection for first-line metastatic renal cell carcinoma in Australia: Impact of new therapy options

Autor: Andrew Weickhardt, Carole A. Harris, Laurence Eliot Miles Krieger, Jeffrey C. Goh, Anthony M. Joshua, Arun Azad, Andrew Schmidt
Rok vydání: 2019
Předmět:
Zdroj: Asia-Pacific journal of clinical oncologyREFERENCES. 15
ISSN: 1743-7563
Popis: Vascular endothelial growth factor receptor tyrosine kinase inhibitors have provided an effective standard of care for the treatment of metastatic clear cell renal cell carcinoma (mRCC). Survival is prolonged with emergence of modern immuno-oncology combination regimens. Prognostic risk assessment is essential for choosing between these therapies to determine the most appropriate first line treatment option, with selection based on International Metastatic RCC Database Consortium Risk Category. We review the current subsidized first line treatments for mRCC in Australia and consider the evidence for treatment selection and sequencing.
Databáze: OpenAIRE
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