Evaluation of diffusion-weighted imaging for the differential diagnosis of poorly contrast-enhanced and T2-prolonged bone masses: Initial experience
| Autor: | Osamu Shimomura, Toshitake Yakushiji, Takeshi Nakaura, Masanori Imuta, Yoshiko Hayashida, Kazuhiro Katahira, Kazuo Awai, Yasuyuki Yamashita, Daisuke Utsunomiya, Toshinori Hirai |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent media_common.quotation_subject Chondrosarcoma Contrast Media Bone Neoplasms Diagnosis Differential Lesion Bone Cysts Humans Medicine Contrast (vision) Effective diffusion coefficient Radiology Nuclear Medicine and imaging Retrospective Studies media_common Analysis of Variance business.industry Fibrous dysplasia Fibrous Dysplasia of Bone Middle Aged Bone masses medicine.disease Diffusion Magnetic Resonance Imaging Female Radiology Bone Diseases medicine.symptom Differential diagnosis business Nuclear medicine Diffusion MRI |
| Zdroj: | Journal of Magnetic Resonance Imaging. 23:377-382 |
| ISSN: | 1522-2586 1053-1807 |
| DOI: | 10.1002/jmri.20512 |
| Popis: | Purpose To determine whether quantitative diffusion-weighted imaging (DWI) is useful for characterizing poorly contrast-enhanced and T2-prolonged bone masses. Materials and Methods We studied 20 bone masses that showed high signal intensity on T2-weighted images and poor enhancement on contrast-enhanced T1-weighted images. These included eight solitary bone cysts, five fibrous dysplasias, and seven chondrosarcomas. To analyze diffusion changes we calculated the apparent diffusion coefficient (ADC) for each lesion. Results The ADC values of the two types of benign lesions and chondrosarcomas were not significantly different. However, the mean ADC value of solitary bone cysts (mean ±SD, 2.57 ± 0.13 × 10–3 mm2/second) was significantly higher than that of fibrous dysplasias and chondrosarcomas (2.0 ± 0.21 × 10–3 mm2/second and 2.29 ± 0.14 × 10–3 mm2/second, respectively, P < 0.05). None of the lesions with ADC values lower than 2.0 × 10–3 mm2/second were chondrosarcomas. Conclusion Although there was some overlapping in the ADC values of chondrosarcomas, solitary bone cyst, and fibrous dysplasia, quantitative DWI may aid in the differential diagnosis of poorly contrast-enhanced and T2-prolonged bone masses. J. Magn. Reson. Imaging 2006. © 2006 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text