Osmotic demyelination syndrome following slow correction of hyponatremia: Possible role of hypokalemia
| Autor: | Sajjad R Bazaz, Umar Hafiz Khan, Sanaullah Shah, Rafi A Jan, Feroze Ahmad, Abdul Baseer Qadri, Mohammed Ashraf, Parvaiz A Koul, Burhan Wani |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Extrapontine myelinolysis Pediatrics hyponatremia business.industry locked-in state nutritional and metabolic diseases Case Report Neurological disorder Critical Care and Intensive Care Medicine medicine.disease Hypokalemia Electrolyte disturbances Concomitant hypokalemia medicine Central pontine myelinolysis medicine.symptom Intensive care medicine business Hyponatremia Electrolyte Disorder |
| Zdroj: | Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine |
| ISSN: | 1998-359X 0972-5229 |
| DOI: | 10.4103/0972-5229.118433 |
| Popis: | A 47-year-old male presented with hyponatremia that was corrected slowly as per the recommended guidelines. The patient improved initially but went on to develop a quadriparesis with a locked-in state due to a central as well as extrapontine myelinolysis and subsequently succumbed to an intercurrent infective illness. The patient had associated hypokalemia. Hyponatremia can result in central pontine myelinolysis even when the electrolyte disorder is treated slowly, and the concomitant hypokalemia seems to play a contributory role in the pathogenesis of the neurological disorder. |
| Databáze: | OpenAIRE |
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