| Autor: |
Ochmann, David T., Philippi, Keito F. A., Zeier, Peter, Sandner, Magdalena, Hillen, Barlo, Neuberger, Elmo W. I., Ruiz De Azua, Inigo, Lieb, Klaus, Wessa, Michele, Lutz, Beat, Simon, Perikles, Brahmer, Alexandra |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
JMIR Research Protocols |
| ISSN: |
1929-0748 |
| Popis: |
Background Physical activity alleviates chronic stress. The latest research suggests a relationship between resilience and physical fitness. Beneficial adaptations of the hypothalamic-pituitary-adrenal axis, sympathetic nervous system, endocannabinoid system, and tryptophan pathway, which are induced by an active lifestyle, are considered to be conducive to resilience. However, detailed knowledge on the molecular link between the effects of acute and chronic physical exercise and improved resilience to stress in humans is missing. Moreover, the relationship between innate and acquired aerobic capacity and resilience is poorly understood. Objective The aim of this study is to implement a human exercise intervention trial addressing the following main hypotheses: a high innate aerobic capacity is associated with high resilience to stress, and web-based physical exercise training improves aerobic capacity of physically inactive adults, which is accompanied by improved resilience. In this setting, we will analyze the relationship between resilience parameters and innate and acquired aerobic capacity as well as circulating signaling molecules. Methods A total of 70 healthy, physically inactive ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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