Fractional carbon dioxide laser versus trichloroacetic acid peel in the treatment of pseudo-acanthosis nigricans
Autor: | Rania Alakad, Fatma Eldeeb, Reham M Wahid |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Erythema medicine.medical_treatment Urology Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Chemexfoliation medicine Humans Acanthosis Nigricans Trichloroacetic acid Trichloroacetic Acid Adverse effect Acanthosis nigricans Co2 laser business.industry Carbon dioxide laser Carbon Dioxide medicine.disease Hyperpigmentation Axilla medicine.anatomical_structure Treatment Outcome chemistry 030220 oncology & carcinogenesis Lasers Gas medicine.symptom business |
Zdroj: | Journal of cosmetic dermatologyREFERENCES. 21(1) |
ISSN: | 1473-2165 |
Popis: | BACKGROUND Treatment of acanthosis nigricans (AN) is challenging, and new modalities are being explored continuously to increase the therapeutic efficacy. AIM To evaluate the efficacy and safety of fractional CO2 laser compared to trichloroacetic acid (TCA) peel in the treatment of pseudo-acanthosis nigricans (pseudo-AN). METHODS The study included 40 patients with pseudo-AN on the neck and axilla allocated into two groups each containing 20 patients. Group (A) was treated with TCA 20% peel applied on the pigmented area while group (B) received fractional CO2 laser. Both treatments were performed till complete clearance or for a maximum of four treatment sessions. Patients with excellent response were further followed up for 6 months after the end of treatment. RESULTS Both modalities were effective in the treatment of pseudo-AN; however, the therapeutic response was significantly higher in the fractional CO2 laser group compared to the TCA peel group (p |
Databáze: | OpenAIRE |
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