Effect of photofunctionalization on titanium bone-implant integration in ovariectomized rats
| Autor: | Shuhei, Kemuriyama, Hideki, Aita, Takeo, Maida, Naohiko, Kawamura, Takashi, Nezu, Masahiro, Iijima, Kazuhiko, Endo, Hisashi, Koshino |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Dental Materials Journal. 42:11-18 |
| ISSN: | 1881-1361 0287-4547 |
| DOI: | 10.4012/dmj.2022-081 |
| Popis: | Osteoporosis is considered a risk factor for osseointegration during implant treatment. Photofunctionalization of titanium has been shown to improve bone-based cell adhesion, proliferation, and functional expression, increasing the bone-implant contact rate and bone-implant integration strength. This study aimed to test the hypothesis that photofunctionalization is effective for implant fixation using an osteoporosis rat model. In the biomechanical push-in test, the bone-implant integration strength of the photofunctionalization treatment group was 1.53 times that of the control group (p0.05). These values implied that photofunctionalization restored the ovariectomy-induced low bone-implant integration strength to normal states. In the micro-CT analysis, the BV/TV of the photofunctionalization treatment group was 1.32 times that of the control group (p0.05). These values implied that photofunctionalization restored the ovariectomy-induced low peri-implant bone formation to normal states. These results indicate that photofunctionalization treatment increased peri-implant bone formation and bone-implant integration strength in ovariectomized rats. |
| Databáze: | OpenAIRE |
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