Interaction effects of cell diffusion, cell density and public goods properties on the evolution of cooperation in digital microbes
| Autor: | Akos Dobay, Daniel J. Rankin, Antonio Messina, Rolf Kümmerli, Homayoun C. Bagheri |
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| Přispěvatelé: | University of Zurich, Dobay, Akos |
| Rok vydání: | 2014 |
| Předmět: |
0106 biological sciences
genetic structures Fitness landscape Cheating media_common.quotation_subject Biology Interaction Models Biological 010603 evolutionary biology 01 natural sciences 03 medical and health sciences 10127 Institute of Evolutionary Biology and Environmental Studies 10126 Department of Plant and Microbial Biology Microbial cooperation Production (economics) Population growth Computer Simulation Function (engineering) Ecology Evolution Behavior and Systematics Industrial organization 030304 developmental biology media_common 0303 health sciences Ecology Public good Biological Evolution 1105 Ecology Evolution Behavior and Systematics Microbial Interactions 570 Life sciences biology 590 Animals (Zoology) |
| Zdroj: | Journal of Evolutionary Biology |
| DOI: | 10.1111/jeb.12437 |
| Popis: | Microbial cooperation typically consists in the sharing of secreted metabolites (referred to as public goods) within the community. Although public goods generally promote population growth, they are also vulnerable to exploitation by cheating mutants, which no longer contribute, but still benefit from the public goods produced by others. Although previous studies have identified a number of key factors that prevent the spreading of cheaters, little is known about how these factors interact and jointly shape the evolution of microbial cooperation. Here, we address this issue by investigating the interaction effects of cell diffusion, cell density, public good diffusion and durability (factors known to individually influence costs and benefits of public goods production) on selection for cooperation. To be able to quantify these effects across a wide parameter space, we developed an individual-based simulation platform, consisting of digital cooperator and cheater bacteria inhabiting a finite two-dimensional continuous toroidal surface. Our simulations, which closely mimic microbial microcolony growth, revealed that: (i) either reduced cell diffusion (which keeps cooperators together) or reduced public good diffusion (which keeps the public goods closer to the producer) is not only essential but also sufficient for cooperation to be promoted; (ii) the sign of selection for or against cooperation can change as a function of cell density and in interaction with diffusion parameters; and (iii) increased public goods durability has opposing effects on the evolution of cooperation depending on the level of cell and public good diffusion. Our work highlights that interactions between key parameters of public goods cooperation give rise to complex fitness landscapes, a finding that calls for multifactorial approaches when studying microbial cooperation in natural systems. |
| Databáze: | OpenAIRE |
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