Plasma Rich in Growth Factors for the Treatment of Dry Eye after LASIK Surgery
| Autor: | Francisco Muruzabal, Ronald M Sanchez-Avila, Gorka Orive, Eduardo Anitua, Maria Laura Fernandez, Luis Alberto Rodriguez-Gutierrez, Nancy Jurado, Jesus Merayo-Lloves |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Visual analogue scale medicine.medical_treatment Keratomileusis Laser In Situ Visual Acuity Keratomileusis Cornea 03 medical and health sciences Cellular and Molecular Neuroscience Plasma 0302 clinical medicine Postoperative Complications Refractive surgery medicine Humans Ocular Surface Disease Index Adverse effect Aged Retrospective Studies Aged 80 and over business.industry LASIK General Medicine Middle Aged eye diseases Sensory Systems Surgery Ophthalmology medicine.anatomical_structure 030221 ophthalmology & optometry Intercellular Signaling Peptides and Proteins Dry Eye Syndromes Female sense organs Ophthalmic Solutions business 030217 neurology & neurosurgery After treatment |
| Zdroj: | Ophthalmic research. 60(2) |
| ISSN: | 1423-0259 |
| Popis: | Purpose: The aim of this study was to evaluate the use of plasma rich in growth factors (PRGF) eye drops in patients with dry eye disease after laser-assisted in situ keratomileusis (LASIK) surgery. Material and Methods: This is a longitudinal, retrospective, comparative, and descriptive study of 77 eyes of 42 patients with dry eye disease following LASIK surgery. This study was designed to evaluate the efficacy of PRGF treatment compared to conventional therapy (control group). Outcome measures including signs and symptoms of dry eye disease were evaluated before and after treatment. The percentage of change before and after treatment for each clinical variable measured was compared between both groups. Results: There were 1–4 treatment cycles with PRGF eye drops (1 cycle = 6 weeks). Results showed a statistically significant improvement in the Ocular Surface Disease Index (38.12%), visual analogue scale scores for frequency (41.89%) and severity (42.47%), and the Schirmer test scores (88.98%) after PRGF treatment (p < 0.05). No adverse events were reported after PRGF treatment. Conclusions: These results suggest that PRGF eye drops are effective for the improvement of dry eye symptoms in patients who underwent LASIK surgery in comparison to the conventional therapy. The treatment with PRGF is an alternative for patients who suffer from postoperative dry eye. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|