Unique blood culture for diagnosis of bloodstream infections in emergency departments: a prospective multicentre study
| Autor: | S, Dargère, J-J, Parienti, E, Roupie, P-E, Gancel, E, Wiel, N, Smaiti, C, Loiez, L-M, Joly, L, Lemée, M, Pestel-Caron, D, du Cheyron, R, Verdon, R, Leclercq, V, Cattoir, Nicolas, Peschanski |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Adolescent Blood contamination bloodstream infection Bacteremia Specimen Handling Hospitals University Young Adult blood cultures Bloodstream infection Internal medicine medicine Humans Blood culture Prospective Studies Intensive care medicine Aged Aged 80 and over Bacteriological Techniques medicine.diagnostic_test business.industry fungi General Medicine Middle Aged University hospital Cost savings Blood Infectious Diseases blood contamination Emergency Medicine Bacteraemia Female France business Emergency Service Hospital |
| Zdroj: | Clinical Microbiology and Infection. 20(11):O920-O927 |
| ISSN: | 1198-743X |
| DOI: | 10.1111/1469-0691.12656 |
| Popis: | Detection of microorganisms by blood cultures (BCs) is essential in managing patients with bacteraemia. Rather than the number of punctures, the volume of blood drawn is considered paramount in efficient and reliable detection of microorganisms. We performed a 1-year prospective multicentre study in adult emergency departments of three French university hospitals comparing two methods for BCs: a unique blood culture (UBC) collecting a large volume of blood (40 mL) and the standard method of multiple blood cultures (MBC). The performances of both methods for bacterial contamination and efficient microbial detection were compared, each patient serving as his own control. Amongst the 2314 patients included, three hundred were positive for pathogens (n = 245) or contaminants (n = 55). Out of the 245 patients, 11 were positive for pathogens by UBC but negative by MBC and seven negative by UBC but positive by MBC (p 0.480). In the subgroup of 137 patients with only two BCs, UBC was superior to MBC (p 0.044). Seven and 17 patients had contaminated BCs by UBC and MBC only, respectively (p 0.062). Considering the sums of pathogens missed and contaminants, UBC significantly outperformed MBC (p 0.045). Considering the complete picture of cost savings, efficient detection of microorganisms and decrease in contaminations, UBC offers an interesting alternative to MBC. |
| Databáze: | OpenAIRE |
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