The Pacific oyster (Crassostrea gigas) Hsp70 modulates the Ostreid herpes virus 1 infectivity
| Autor: | Carolina Gallardo-Ybarra, José Manuel Grijalva-Chon, Reina Castro-Longoria, Arturo Sánchez-Paz, Amir Darío Maldonado-Arce, Marco Antonio López-Torres, Manuel Adolfo Lastra-Encinas, Enrique de-la-Re-Vega |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Oyster 030106 microbiology Zoology Aquatic Science Biology Virus 03 medical and health sciences biology.animal Environmental Chemistry Animals HSP70 Heat-Shock Proteins Crassostrea Gene Pathogen Infectivity Ecology DNA Viruses Genetic Variation General Medicine Pacific oyster biology.organism_classification Immunity Innate Salinity 030104 developmental biology Gene Expression Regulation |
| Zdroj: | Fishshellfish immunology. 71 |
| ISSN: | 1095-9947 |
| Popis: | The Ostreid herpes virus type 1 (OsHV-1) is one of the most devastating pathogen in oyster cultures. Among several factors, as food limitation, oxygen depletion, salinity and temperature variations, episodes of “summer mortality” of the Pacific oyster Crassostrea gigas have also been associated with OsHV-1 infection. Mortalities of C. gigas spat and juveniles have increased significantly in Europe, and contemporary mortality records of this mollusk in Mexico have been associated with the occurrence of OsHV-1. In the present study, the expression of the heat shock protein 70 gene from the Pacific oyster correlates with the abundance of DNA polymerase transcripts from the OsHV-1. This may suggest that the induction on the expression of the Pacific oyster hsp70 may potentially participate in the immune response against the virus. Furthermore, this study reports for the first time a TEM representative image of the OsHV-1 in aqueous solution, which possesses an icosahedral shape with a diameter of 70 nm × 100 nm. Finally, the examined sequence encoding the ORF4 of the OsHV-1 isolate from northwest Mexico showed specific sequence variations when compared with OsHV-1 isolates from distant geographical areas. |
| Databáze: | OpenAIRE |
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