Predictors of death in severe COVID-19 patients at millennium COVID-19 care center in Ethiopia: a case-control study
| Autor: | Abdi Bekele Banegyisa, Wondmagegn Genaneh Shiferaw, Ishmael S. Hassen, Teketel T. Admasu, Wuletaw C. Zewde, Endalkachew H. Maru, Oli Seyoum Tefera, Negat W Chamiso, Tariku B. Jagema, Daniel S. Abebe, Tigist W. Leulseged, Mesfin Abebe Gezahegn |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty 2019-20 coronavirus outbreak COVID-19 death predictors case-control logistic regression Ethiopia Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Discharged alive Logistic regression Severity of Illness Index Diabetes mellitus medicine Humans Favorable outcome Aged business.industry Research Case-control study Care center General Medicine Odds ratio Middle Aged medicine.disease Prognosis Confidence interval Hospitals Case-Control Studies Female business |
| Zdroj: | The Pan African Medical Journal Pan African Medical Journal; Vol. 38 No. 1 (2021) |
| ISSN: | 1937-8688 |
| Popis: | BackgroundAs the number of new cases and death due to COVID-19 is increasing, understanding the characteristics of severe COVID-19 patients and identifying characteristics that lead to death is a key to make an informed decision. In Ethiopia, as of September 27, 2020, a total of 72,700 cases and 1165 deaths were reported.ObjectiveThe study aimed to assess the determinants of death in Severe COVID-19 patients admitted to Millennium COVID-19 Care Center in Ethiopia.MethodsA case-control study of 147 Severe COVID-19 patients (49 deaths and 98 discharged alive cases) was conducted from August to September 2020. A comparison of underlying characteristics between cases (death) and controls (alive) was assessed using a chi-square test and an independent t-test with a p-value of ResultsHaving diabetes mellitus (AOR= 3.257, 95% CI= 1.348, 7.867, p-value=0.00), fever (AOR=0.328, 95% CI: 0.123, 0.878, p-value= 0.027) and Shortness of breath (AOR= 4.034, 95% CI= 1.481, 10.988, p-value=0.006) were found to be significant predictors of death in Severe COVID-19 patients.ConclusionsThe outcome of death in Severe COVID-19 patients is found to be associated with exposures to being diabetic and having SOB at admission. On the other hand, having a fever at admission was associated with a favorable outcome of being discharged alive. |
| Databáze: | OpenAIRE |
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