Autoregulation of iclR, the gene encoding the repressor of the glyoxylate bypass operon
| Autor: | Bin Pan, David C. LaPorte, Alden Sunnarborg, Lizhen Gui |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
DNA
Bacterial Transcription Genetic Operon Recombinant Fusion Proteins Molecular Sequence Data lac operon Repressor Protein Serine-Threonine Kinases Biology Binding Competitive Microbiology Bacterial Proteins Transcription (biology) Malate synthase Promoter Regions Genetic Molecular Biology Gene Sequence Deletion Regulation of gene expression Base Sequence Escherichia coli Proteins Malate Synthase Glyoxylates Promoter Gene Expression Regulation Bacterial beta-Galactosidase Isocitrate Lyase Molecular biology Repressor Proteins Genes Bacterial biology.protein Research Article Transcription Factors |
| Zdroj: | Journal of Bacteriology. 178:321-324 |
| ISSN: | 1098-5530 0021-9193 |
| DOI: | 10.1128/jb.178.1.321-324.1996 |
| Popis: | The aceBAK operon was partially induced by a multicopy plasmid which carried the promoter region of the gene which encodes its repressor, iclR. Gel shift and DNase I analyses demonstrated that IclR binds to its own promoter. Disruption of iclR increased the expression of an iclR::lacZ operon fusion. Although aceBAK and iclR are both regulated by IclR, aceBAK expression responds to the carbon source, while expression of iclR does not. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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