Sudden Death Due to Ventricular Septal Defect
| Autor: | Stephen D. Cohle, Michael Bell, Elizabeth Balraj |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Heart Septal Defects
Ventricular Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Cardiomegaly Pulmonary Artery Sudden death Unexpected death Pathology and Forensic Medicine Diagnosis Differential 03 medical and health sciences Fatal Outcome 0302 clinical medicine Smooth muscle Internal medicine Humans Medicine Heart septal defect 030219 obstetrics & reproductive medicine business.industry Infant Newborn Clinical course Infant Common denominator General Medicine medicine.disease Surgery 030220 oncology & carcinogenesis Heart failure Cardiac hypertrophy Pediatrics Perinatology and Child Health Cardiology Female business Sudden Infant Death |
| Zdroj: | Pediatric and Developmental Pathology. 2:327-332 |
| ISSN: | 1615-5742 1093-5266 |
| Popis: | Ventricular septal defects (VSD) are usually considered non-life-threatening, usually closing spontaneously or causing symptoms of congestive heart failure, which can be surgically treated in time to save the patient's life. Despite the usually benign clinical course of VSD, serious arrhythmias occur in 16–31% of patients. Sudden death accounted for one-third of all deaths in a series of medically managed patients and occurred in 4.2% of patients in a study of VSD and arrhythmias. Cardiac hypertrophy is the common denominator in all cases reported in detail of VSD-associated sudden death. We have encountered four cases of sudden unexpected death from VSD in infants ranging in age from 1 week to 3 and ½ months. In each case there was cardiomegaly and in one case there was pulmonary arteriolar medial thickening, with extension of smooth muscle into small intralobular vessels. In half of our cases the attending physician was sued for malpractice. We believe that VSD in infants and young children are potentially life-threatening malformations which warrant careful clinical follow-up. |
| Databáze: | OpenAIRE |
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