Neuroleptic Malignant Syndrome: Two Cases without Muscle Rigidity
| Autor: | Michael M.C. Wong |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Psychosis Hallucinations 03 medical and health sciences 0302 clinical medicine medicine Humans Neuroleptic Malignant Syndrome 030212 general & internal medicine Psychomotor Agitation Neurologic Examination Skeletal muscle General Medicine medicine.disease Pathophysiology Bromocriptine Muscle Rigidity 030227 psychiatry Peripheral Neuroleptic malignant syndrome Psychiatry and Mental health medicine.anatomical_structure Schizophrenia Anesthesia Psychology Antipsychotic Agents medicine.drug |
| Zdroj: | Australian & New Zealand Journal of Psychiatry. 30:415-418 |
| ISSN: | 1440-1614 0004-8674 |
| DOI: | 10.3109/00048679609065008 |
| Popis: | Objective: Two patients with neuroleptic malignant syndrome without muscle rigidity are described. Clinical picture: Both patients developed fever and altered consciousness while taking neuroleptic but did not develop muscle rigidity; the symptoms subsided when the neuroleptic was stopped but recurred when it was given again. Treatment: The neuroleptic was stopped; one patient received supportive treatment and the other received bromocriptine. Outcome: One patient died while the other survived. Conclusion: The pathophysiology is proposed as a combination of involvement of the central thermoregulatory, neuroregulatory and autonomic nervous systems, and the peripheral skeletal muscle. It supports the concept of a spectrum of clinical severity of neuroleptic malignant syndrome. |
| Databáze: | OpenAIRE |
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