Use of partial least squares path modelling to assess the willingness of Chinese female sex workers to participate in a microbicide trial
| Autor: | M.Y. Shao, H.Y. Ruan, N.X. Zhong, Dexin Li, N. Yao, L.A. Huang, Q. Zeng |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
China media_common.quotation_subject Models Psychological Young Adult Anti-Infective Agents Surveys and Questionnaires Environmental health Microbicide medicine Humans Confidentiality Least-Squares Analysis Social isolation media_common Clinical Trials as Topic Sex Workers business.industry Public Health Environmental and Occupational Health General Medicine Exploratory factor analysis Microbicides for sexually transmitted diseases Clinical trial Cross-Sectional Studies Harm Female Patient Participation medicine.symptom business Welfare |
| Zdroj: | Public Health. 129:1187-1193 |
| ISSN: | 0033-3506 |
| Popis: | Objectives To investigate the willingness of Chinese female sex workers (FSWs) to participate (WTP) in a clinical trial of microbicides; to explore the potential hindrances and facilitating factors; and to provide support for future microbicide clinical trials by tailoring their design to better meet the specific needs of FSWs. Study design Cross-sectional study. Methods In total, 404 FSWs were investigated using structured questionnaires. Exploratory factor analysis and partial least squares path modelling were used to explore the correlations between several influencing factors and WTP. Results The WTP of FSWs enrolled in this study was high (53.47%, 216/404). Possible benefits from enrolment in the trial were positively associated with WTP, while concern about a hypothetical microbicide, potential physical harm, economic loss from participation, and fear of family or social isolation were negatively associated with WTP. Conclusion FSWs are appropriate participants in microbicide clinical trials, and are likely to benefit from effective microbicides. In a microbicide clinical trial, it is imperative to ensure protection of the rights, dignity, safety, confidentiality and welfare of FSW participants. |
| Databáze: | OpenAIRE |
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