Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22
Autor: | Judith A. Hartz, Renata Horton, Yale Nemerson, Steven D. Carson, Fa Ten Kao |
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Rok vydání: | 1988 |
Předmět: | |
Zdroj: | Somatic Cell and Molecular Genetics. 14:407-410 |
ISSN: | 1572-9931 0740-7750 |
DOI: | 10.1007/bf01534649 |
Popis: | Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes. |
Databáze: | OpenAIRE |
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