Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22

Autor: Judith A. Hartz, Renata Horton, Yale Nemerson, Steven D. Carson, Fa Ten Kao
Rok vydání: 1988
Předmět:
Zdroj: Somatic Cell and Molecular Genetics. 14:407-410
ISSN: 1572-9931
0740-7750
DOI: 10.1007/bf01534649
Popis: Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.
Databáze: OpenAIRE