Modification of the biophysical characteristics of membranes incommensalEscherichia colistrains from breast cancer patients
| Autor: | Armen Trchounian, Natella Mirzoyan, Astghik Z. Pepoyan |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Breast Neoplasms
Biology medicine.disease_cause Microbiology Membrane Potentials H(+)-K(+)-Exchanging ATPase Escherichia coli Genetics medicine Humans Anaerobiosis Molecular Biology Ion transporter chemistry.chemical_classification Membrane potential Ion Transport Strain (chemistry) Cell Membrane Cancer medicine.disease Aerobiosis In vitro Intestines Enzyme Biochemistry chemistry Potassium Female Fermentation Hydrogen |
| Zdroj: | FEMS Microbiology Letters. 254:81-86 |
| ISSN: | 1574-6968 0378-1097 |
| Popis: | Escherichia coli G35 N49 strain, from the gut of breast cancer patients, in comparison with the E. coli G35 N61 strain, from the gut of healthy people, shows in vitro reduction in growth rates and maximal growth yield. The changes in certain membrane characteristics, such as low membrane potential and disturbance in intramembrane interaction of H+ -ATPase F0F1 with the TrkA system, indicate a dysfunction in ion transport and enzymatic activity. These changes can be detected during fermentation and in anaerobic conditions (in the gut, for example) and may be influenced by unfavorable conditions in the gut of cancer patients. |
| Databáze: | OpenAIRE |
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