Localization of calcitonin gene-related peptide in the organ of Corti of the rat: an immunohistochemical study
| Autor: | Piers C. Emson, Masaya Tohyama, Sadao Shiosaka, Yasushi Kawasaki, I. MacIntyre, Tadami Kumazawa, S. Girgis, Masanori Kitajiri, C.J. Hillyard, Toshio Yamashita, Toru Matsunaga, Y. Tohyama, Noriaki Takeda |
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| Rok vydání: | 1985 |
| Předmět: |
Male
Pathology medicine.medical_specialty Auditory Pathways Calcitonin Gene-Related Peptide Immunocytochemistry Fluorescent Antibody Technique Nerve Tissue Proteins Olivary Nucleus Calcitonin gene-related peptide Biology otorhinolaryngologic diseases medicine Animals Cochlear Nerve Organ of Corti Molecular Biology Cochlea General Neuroscience Anatomy Rats Ganglion medicine.anatomical_structure Calcitonin Superior olivary complex Immunohistochemistry sense organs Neurology (clinical) Developmental Biology |
| Zdroj: | Brain Research. 358:394-397 |
| ISSN: | 0006-8993 |
| DOI: | 10.1016/0006-8993(85)90992-8 |
| Popis: | The localization of calcitonin gene-related peptide (CGRP)-like immunoreactive (CGRPI) structures in the cochlea was examined in the rat using immunocytochemistry. Numerous CGRPI fibers entered the organ of Corti in the intraganglionic spiral bundle and formed a dense fiber patch at the base of the inner hair cells. Much fewer, but still a significant number of CGRPI fibers were seen at the synaptic region of the outer hair cells. Since no immunoreactive cells were seen in the organ of Corti and spinal ganglion, these fibers may be one of the major components of the olivocochlear bundles originated from the superior olivary complex. |
| Databáze: | OpenAIRE |
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