Automation of intraoperative analysis of indicators the inflammatory response of neurosurgical patients undergoing brain tumors removal
| Autor: | Sergey Sokolov, Nataliya Dragina, Anatoliy Kondratiev, Nataliya Lesteva |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
biology
business.industry 030208 emergency & critical care medicine 02 engineering and technology Perioperative Prolactin Clonidine Fentanyl Environmental sciences 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Posterior cranial fossa Hemostasis Anesthesia 0202 electrical engineering electronic engineering information engineering medicine biology.protein GE1-350 020201 artificial intelligence & image processing Propofol business Interleukin 6 medicine.drug |
| Zdroj: | E3S Web of Conferences, Vol 258, p 04005 (2021) |
| ISSN: | 2267-1242 |
| Popis: | The data of the study of indicators of the inflammatory response, hormonal status, biochemical blood parameters in the perioperative period in neurosurgical patients undergoing surgery for tumors of the posterior cranial fossa are presented. This study included 65 patients. The surgery was performed under anesthesia with fentanyl (3-5 µg / kg-hour), clonidine (1-2 µg / kg-hour), and propofol (3-5 mg / kg-hour). A significant increase in the level of interleukin 10 was observed at the level of hemostasis. The day after surgery, the level of Interleukin 6 increased significantly. During hemostasis, there was a temporary increase in ACTH, cortisol, and prolactin levels. The day after the surgery, rates returned to their original levels. Under conditions of persistent neurovegetative, a sufficient humoral response to surgical trauma was noted. |
| Databáze: | OpenAIRE |
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