Impact of inflammation and oxidative stress on carotid intima-media thickness in obstructive sleep apnea patients without metabolic syndrome

Autor:	Ting-Yao Chen, Cheng-Hsien Lu, Chih-Cheng Huang, Chih-Min Su, Hsin-Ching Lin, Ben-Chung Cheng, Chia-Te Kung, Yi-Fang Chiang, Hung-Chen Wang, Wei-Che Lin, Nai-Wen Tsai, Yu-Jih Su, Ya-Ting Chang, Wen-Neng Chang
Rok vydání:	2016
Předmět:	Adult Male medicine.medical_specialty Aging Cognitive Neuroscience Blood Pressure Polysomnography 030204 cardiovascular system & hematology Carotid Intima-Media Thickness 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Internal medicine medicine Humans cardiovascular diseases Sulfhydryl Compounds Inflammation Metabolic Syndrome Sleep disorder Sleep Apnea Obstructive medicine.diagnostic_test business.industry Apnea General Medicine medicine.disease Intercellular Adhesion Molecule-1 respiratory tract diseases Obstructive sleep apnea Oxidative Stress Blood pressure Intima-media thickness cardiovascular system Cardiology Female medicine.symptom Metabolic syndrome business Lipoproteins HDL Hypopnea 030217 neurology & neurosurgery
Zdroj:	Journal of sleep research. 26(2)
ISSN:	1365-2869
Popis:	Summary Obstructive sleep apnea (OSA) increases the risk of cardiovascular diseases, and carotid intima-media thickness (IMT) is a good indicator of the severity of atherosclerotic disease. This study tested the hypothesis that inflammation and oxidative stress determined carotid IMT in patients with OSA. The carotid IMT, mean systolic and diastolic pressure (night and morning) were significantly higher and the level of thiols and high-density lipoprotein were significantly lower in our 121 OSA patients than in 27 controls (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaeb983846079eecbf376d19b72b74da https://pubmed.ncbi.nlm.nih.gov/27896929 Zobrazit plný text záznamu Plný text