Tolperisone in the treatment of acute and chronic nonspecific back pain
| Autor: | O. E. Zinovyeva, V. L. Golubev, A. A. Golovacheva, V. A. Golovacheva |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Tolperisone
medicine.drug_class back pain tolperisone law.invention 03 medical and health sciences 0302 clinical medicine Pharmacotherapy Randomized controlled trial law medicine Back pain 030212 general & internal medicine RC346-429 treatment business.industry Chronic pain acute pain Muscle relaxant medicine.disease Clinical trial Psychiatry and Mental health Clinical Psychology Stenosis Anesthesia muscle relaxants Neurology. Diseases of the nervous system Neurology (clinical) medicine.symptom chronic pain business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Nevrologiâ, Nejropsihiatriâ, Psihosomatika, Vol 12, Iss 4, Pp 137-142 (2020) |
| ISSN: | 2310-1342 2074-2711 |
| DOI: | 10.14412/2074-2711-2020-4-137-142 |
| Popis: | Nonspecific back pain (NBP) is one of the most common reasons to see a neurologist or therapist. Acute (12 weeks) NBPs are recognized. The diagnosis of NBP is based on anamnestic data, somatic, neurological, and neurologic-and-orthopedic examination findings and on the exclusion of the specific causes of back pain, discogenic radiculopathy, and vertebral canal stenosis. Nonsteroidal anti-inflammatory drugs (NSAIDs) and muscle relaxants are used in the pharmacotherapy of acute, subacute, and chronic NBP. Tolperisone is widely used as a muscle relaxant in Russia and in the countries of Europe and Asia. Clinical trials have shown the efficacy and good tolerance of tolperisone used alone and in combination with NSAIDs for NBP. The review presents clinical recommendations from different countries on the use of muscle relaxants in the treatment of acute and chronic NBP. It is concluded that a large-scale qualitative randomized trial should be conducted to investigate the efficacy of muscle relaxants, tolperisone in particular, in the treatment of acute, subacute, and chronic NBP. |
| Databáze: | OpenAIRE |
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