Effects of Bovine Follicular Fluid on Pulsatile Secretion of Gonadotrophin-Releasing Hormone and Gonadotrophins in Ovariectomized Ewes
| Autor: | Jiang‐yuan ‐y Li, Lain J. Clarke, Heather Francis |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
endocrine system
medicine.medical_specialty Pituitary gland Endocrine and Autonomic Systems Chemistry Endocrinology Diabetes and Metabolism Gonadotropic cell Follicular fluid Cellular and Molecular Neuroscience Follicle-stimulating hormone Endocrinology medicine.anatomical_structure Internal medicine Follicular phase Ovariectomized rat medicine Luteinizing hormone hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Journal of Neuroendocrinology. 1:61-64 |
| ISSN: | 1365-2826 0953-8194 |
| DOI: | 10.1111/j.1365-2826.1989.tb00077.x |
| Popis: | Ovariectomized ewes were injected with charcoal-extracted bovine follicular fluid (n = 5) or with hypophysectomized ewe serum (n = 5) after which hypophyseal portal blood samples were taken to monitor the release of gonadotrophin-releasing hormone (GnRH). Peripheral blood samples were also taken to monitor plasma luteinizing hormone and follicle-stimulating hormone (FSH) concentrations. Bovine follicular fluid treatment caused a 50% decrease in plasma FSH concentrations whereas hypophysectomized ewe serum did not significantly alter plasma FSH levels. The frequency and amplitude of luteinizing hormone and GnRH pulses was similar in both experimental groups. It is concluded that inhibin activity in bovine follicular fluid selectively suppresses the release of FSH by direct action on the pituitary gland, with no effect on GnRH secretion. |
| Databáze: | OpenAIRE |
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