Implications of Transcranial Magnetic Stimulation as a Treatment Modality for Tinnitus
| Autor: | Adrien A. Eshraghi, Fred F. Telischi, Tricia Scaglione, Brianna Kuzbyt, Peter E. Ashman, Ariel Finberg, Alexa J. Denton, Rahul Mittal, Nathalie B Bencie |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment non-invasive Stimulation Review Audiology Auditory cortex Neuroplasticity medicine auditory cortex tinnitus synaptic plasticity business.industry General Medicine Neuromodulation (medicine) Transcranial magnetic stimulation Dorsolateral prefrontal cortex medicine.anatomical_structure Treatment modality TMS neuromodulation Medicine medicine.symptom business Tinnitus |
| Zdroj: | Journal of Clinical Medicine, Vol 10, Iss 5422, p 5422 (2021) Journal of Clinical Medicine |
| ISSN: | 2077-0383 |
| Popis: | Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive, neuromodulating technique for brain hyperexcitability disorders. The objective of this paper is to discuss the mechanism of action of rTMS as well as to investigate the literature involving the application of rTMS in the treatment of tinnitus. The reviewed aspects of the protocols included baseline evaluation, the total number of sessions, frequency and the total number of stimuli, the location of treatment, and the outcome measures. Even with heterogeneous protocols, most studies utilized validated tinnitus questionnaires as baseline and outcome measures. Low frequency (1 Hz) stimulation throughout 10 consecutive sessions was the most widely used frequency and treatment duration; however, there was no consensus on the total number of stimuli necessary to achieve significant results. The auditory cortex (AC) was the most targeted location, with most studies supporting changes in neural activity with multi-site stimulation to areas in the frontal cortex (FC), particularly the dorsolateral prefrontal cortex (DLPFC). The overall efficacy across most of the reviewed trials reveals positive statistically significant results. Though rTMS has proven to impact neuroplasticity at the microscopic and clinical level, further studies are warranted to demonstrate and support the clinical use of rTMS in tinnitus treatment with a standardized protocol. |
| Databáze: | OpenAIRE |
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