Neurocognitive Development and Behavioral Outcome of 2-Year-Old Children with Univentricular Heart

Autor: Eero Jokinen, Leena Mildh, Riina Puosi, Anne Sarajuuri, Ilkka P. Mattila, Marit Korkman, Tuula Lönnqvist
Rok vydání: 2011
Předmět:
Zdroj: Journal of the International Neuropsychological Society. 17:1094-1103
ISSN: 1469-7661
1355-6177
DOI: 10.1017/s135561771100110x
Popis: Recent advances in the treatment of children with severe congenital heart defects, such as hypoplastic left heart syndrome (HLHS) and other forms of univentricular heart (UVH), have significantly improved their survival rates. However, these children are at risk for various neurodevelopmental deficits. The aim of the present study was to assess cognitive development, expressive language, and behavior in 30-month-old children with univentricular heart. The participants were 22 children with HLHS, 14 with UVH, and 41 healthy control subjects. The Bayley Scales of Infant Development II, MacArthur Communicative Development Inventories, and Child Behavior Checklist were used for assessments. The results revealed that children with HLHS exhibited a significantly lower mean mental development index, more delays in expressive language functions, and more behavioral problems than did the control children. Two children with HLHS (9%) had mental development indexes below 50, indicating significantly delayed performance. The children with UVH differed from the control children with respect to their lower mean mental development index. These findings suggest that at the age of 30 months, neurodevelopmental deficits are especially prevalent in children with HLHS. Thus, early developmental screening, intervention, and neuropsychological follow-up until school age is recommended particularly for the children with HLHS. (JINS, 2011,17, 1094–1103)
Databáze: OpenAIRE