The Demonstration of Pulmonary Neuroendocrine Cell Hyperplasia with Tumorlets in a Patient with Chronic Cough and a History of Multiple Medical Problems
| Autor: | Lisa L. Zacher, Mark G. Carmichael |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Pathology
medicine.medical_specialty Lung Neoplasms Comorbidity Lung biopsy Air trapping Pulmonary function testing Sleep Apnea Syndromes Bronchoscopy medicine Humans Medical history Sinusitis Lung Hyperplasia medicine.diagnostic_test business.industry Smoking Public Health Environmental and Occupational Health Chronic sinusitis General Medicine Middle Aged Asthma respiratory tract diseases Neuroendocrine Tumors Chronic cough Bronchoalveolar lavage Cough Chronic Disease Gastroesophageal Reflux Female medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Military Medicine. 170:439-441 |
| ISSN: | 1930-613X 0026-4075 |
| DOI: | 10.7205/milmed.170.5.439 |
| Popis: | A 58-year-old woman presented with chronic cough felt to be multifactorial secondary to asthma, gastroesophageal reflux disease, and chronic sinusitis. Additional medical history included obstructive sleep apnea, type 2 diabetes, and hypertension. She had a 40- year history of tobacco use, but quit 10 years ago. Her examination was significant for obesity and cobble stoning of the oropharynx. Pulmonary function testing and arterial blood gases were unrevealing. Chest films were normal. High-resolution computed tomography revealed multiple focal lucencies in a mosaic pattern consistent with air trapping and small airways disease. Bronchoscopy revealed normal airways and a noninflammatory bronchoalveolar lavage. Transbronchial biopsies revealed inflammatory infiltrates of the peribronchiolar interstitium. Lung biopsy revealed pulmonary neuroendocrine cell hyperplasia with tumorlets that stained positive for neuroendocrine tissue. We present the case of a woman with chronic cough, multiple medical problems, and pulmonary neuroendocrine cell hyperplasia with tumorlets. |
| Databáze: | OpenAIRE |
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