Epidemiology and in vitro antimicrobial susceptibility of aerobic Actinomycetales in a clinical setting
| Autor: | Ana Ponz, Marta Martín-García, Alicia Macías-Valcayo, Jaime Esteban, Llanos Salar-Vidal |
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| Rok vydání: | 2022 |
| Předmět: |
0301 basic medicine
Microbiology (medical) food.ingredient medicine.drug_class 030106 microbiology Antibiotics Gordonia sputi Gordonia Nocardia Microbiology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine food Anti-Infective Agents Actinomycetales medicine Humans 030212 general & internal medicine Mycobacterium Infections biology Linezolid biology.organism_classification chemistry Amikacin medicine.drug Mycobacterium |
| Zdroj: | Enfermedades Infecciosas y Microbiología Clínica. 40:562-567 |
| ISSN: | 0213-005X |
| Popis: | Introduction The incidence of infections caused by aerobic actinomycetes is increasing. Recent changes in taxonomy and the variability in susceptibility patterns among species make necessary a proper identification and antibiotic susceptibility testing. Material and methods Fifty-three strains of aerobic actinomycetes were identified by MALDI-TOF MS using the VITEK MS Mycobacterium/Nocardia kit (bioMerieux, France) in a tertiary hospital in Spain during a six-year period. Antimicrobial susceptibility testing of the isolates was performed using the Sensititre Rapmycoi microdilution panel (Thermo Fisher Scientific, Massachusetts, USA). Results Forty strains of Nocardia spp. were identified in the study, being N. farcinica and N. cyriacigeorgica the most prevalent ones. All isolates were susceptible to linezolid and the resistance to amikacin was only observed in one isolate of Gordonia sputi. Resistance to cotrimoxazole was only found in five isolates. Conclusions Routine identification and antimicrobial susceptibility testing of aerobic actinomycetes is advisable for an efficient identification of species and effective treatment. |
| Databáze: | OpenAIRE |
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