Effect of Neonatal Thymectomy and Antithymocytic Serum on Susceptibility of Rats to Mycobacterium leprae Infection
| Autor: | McIntosh Ah, A H Fieldsteel |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Male
Time Factors medicine.medical_treatment Thymus Gland Biology General Biochemistry Genetics and Molecular Biology Mice Testis medicine Lewis rats Animals Neonatal thymectomy Antilymphocyte Serum Mycobacterium Infections Inoculation Rats Inbred Strains Mycobacterium leprae infection Thymectomy Hindlimb Rats Mycobacterium leprae Animals Newborn Immunology Female Rabbits |
| Zdroj: | Experimental Biology and Medicine. 138:408-413 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-138-35908 |
| Popis: | SummaryNeonatal thymectomy and neonatal thymectomy plus ATS resulted in a marked increase in susceptibility of both Buffalo and Lewis rats to infection with M. leprae. In Buffalo rats, increase in susceptibility was limited to footpad infection. In Lewis rats, this was extended to include testis infection where the organisms in thymectomized—ATS-treated rats were found to be still in the logarithmic phase of growth 15 months after inoculation. |
| Databáze: | OpenAIRE |
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