Health related quality of life impact from rotavirus diarrhea on children and their family caregivers in Thailand
| Autor: | Maarten J. Postma, Onwipa Rochanathimoke, Arthorn Riewpaiboon, Montarat Thavorncharoensap, Wirawan Thinyounyong |
|---|---|
| Přispěvatelé: | Microbes in Health and Disease (MHD), Methods in Medicines evaluation & Outcomes research (M2O), PharmacoTherapy, -Epidemiology and -Economics, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Diarrhea
Male medicine.medical_specialty Pediatrics INFANTS medicine.disease_cause Severity of Illness Index Rotavirus Infections 03 medical and health sciences 0302 clinical medicine Quality of life (healthcare) EQ-5D Surveys and Questionnaires 030225 pediatrics Rotavirus Environmental health ACUTE GASTROENTERITIS Epidemiology Journal Article Humans Medicine EPIDEMIOLOGY Pharmacology (medical) 030212 general & internal medicine UK Health related quality of life UTILITY business.industry Family caregivers SCORES Health Policy MORTALITY Infant General Medicine Acute gastroenteritis Thailand Hospitalization Cross-Sectional Studies Caregivers INFECTIONS Child Preschool Quality of Life Regression Analysis Female medicine.symptom business BURDEN |
| Zdroj: | Expert review of pharmacoeconomics & outcomes research, 18, 215-222. Taylor & Francis Group |
| ISSN: | 1473-7167 |
| Popis: | BACKGROUND: Rotavirus diarrhea is a major health problem among young children worldwide with potential negative impacts on health-related quality of life (HRQoL). This study assessed the impact of rotavirus diarrhea on HRQoL of children and their caregivers.METHODS: We performed a cross-sectional study among 460 hospitalized children with diarrhea aged under 5 years and their family caregivers at three hospitals in Phetchabun province, Thailand during May 2013 and February 2014. The severity of diarrhea was assessed using the Vesikari severity scoring system while the HRQoL was assessed using the EQ-5D-3L.RESULTS: The mean EQ-5D utility of children with all-causes diarrhea was 0.604. The utility of the rotavirus diarrhea group was significantly lower than that of the non-rotavirus diarrhea group (0.593 vs. 0.612; p-value = 0.040). The family caregiver's utility was 0.964 at baseline and significantly decreased to 0.620 (p-value = 0.041) when their children were hospitalized with diarrhea. In multiple regression analyses, severity but not rotavirus infection had significant negative impacts on the utility of both the children and their caregivers.CONCLUSION: Diarrhea, either caused by rotavirus or non-rotavirus infection, resulted in substantial negative impacts on the quality of life of both the children and their caregivers. |
| Databáze: | OpenAIRE |
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