Buglossoides spp. seeds, a land source of health-promoting n-3 PUFA and phenolic compounds

Autor: Tarik Chileh Chelh, Svetlana Lyashenko, Abdallah Lahlou, El-Hassan Belarbi, Miguel Ángel Rincón-Cervera, Ignacio Rodríguez-García, Miguel Urrestarazu-Gavilán, Rosalía López-Ruiz, José Luis Guil-Guerrero
Rok vydání: 2022
Předmět:
Zdroj: Food Research International. 157:111421
ISSN: 0963-9969
DOI: 10.1016/j.foodres.2022.111421
Popis: Ahiflower oil© is extracted from the seeds of Buglossoides arvensis, which contains high amounts of stearidonic acid (SDA, 18:4n-3), while its phenolic composition still is unreported. Moreover, several Buglossoides taxa remain unstudied and could become natural sources of SDA. In this work, seeds of several Buglossoides taxa and Ahiflower oil© were screened for fatty acids, phenolic compounds, and in vitro antiproliferative activities against colorectal cancer cells. Four flavonoids and 16 phenolic acids were identified and quantified. Among Buglossoides taxa, the highest amounts of phenolic compounds were found in samples collected in Spain, under a warm Mediterranean climate. Rosmarinic and lithospermic acids were the main phenols found in Buglossoides seeds. The MTT assay showed dose- and time-dependent inhibitory effects of B. arvensis extracts on HT-29 cancer cells, with a GI
Databáze: OpenAIRE