Expression of Indoleamine 2,3-Dioxygenase Gene Is a Feature of Poorly Differentiated Non-muscle-invasive Urothelial Cell Bladder Carcinomas

Autor:	Chantal Mengus, Zeljko Kastelan, Tvrtko Hudolin, Julie Coulot, Ahmad El-Saleh, Giulio C. Spagnoli
Rok vydání:	2016
Předmět:	Male Cancer Research Urothelial Cell 030232 urology & nephrology Kaplan-Meier Estimate Real-Time Polymerase Chain Reaction Gene Expression Regulation Enzymologic law.invention 03 medical and health sciences 0302 clinical medicine law Gene expression Carcinoma medicine Humans Indoleamine-Pyrrole 2 3 -Dioxygenase Stage (cooking) Indoleamine 2 3-dioxygenase Gene Polymerase chain reaction Aged business.industry Gene Expression Profiling Cancer General Medicine Middle Aged medicine.disease Prognosis Gene Expression Regulation Neoplastic Treatment Outcome Oncology Urinary Bladder Neoplasms 030220 oncology & carcinogenesis Multivariate Analysis Cancer research Female Urothelium business Immunosuppressive Agents
Zdroj:	Anticancer research. 37(3)
ISSN:	1791-7530
Popis:	AIM To evaluate indoleamine 2,3-dioxygenase (IDO) gene expression in non-muscle-invasive urothelial cell bladder carcinoma (NMIBC). PATIENTS AND METHODS Seventy-four patients undergoing surgical treatment for NMIBC were enrolled in the study. IDO gene expression was assessed by quantitative real-time polymerase chain reaction (qRT-PCR). RESULTS IDO gene expression was detectable significantly more frequently (48/74, 64.86% vs. 5/21, 23.81%, p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad03b63fc95b8bdbb0440097d85366d https://pubmed.ncbi.nlm.nih.gov/28314306 Zobrazit plný text záznamu