Confocal Laser Endomicroscopy in the Evaluation of Inflammatory Bowel Disease
| Autor: | Anna M. Buchner |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty Inflammatory bowel disease Endoscopy Gastrointestinal medicine Endomicroscopy Animals Humans Immunology and Allergy Irritable bowel syndrome Crohn's disease Microscopy Confocal medicine.diagnostic_test business.industry fungi Gastroenterology Mucous membrane Inflammatory Bowel Diseases medicine.disease Ulcerative colitis digestive system diseases Endoscopy medicine.anatomical_structure Evaluation Studies as Topic Dysplasia business |
| Zdroj: | Inflammatory Bowel Diseases. 25:1302-1312 |
| ISSN: | 1536-4844 1078-0998 |
| Popis: | Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, can be effectively monitored with the use of endoscopy. The additional application of small field imaging technology such as confocal laser endomicroscopy CLE during ongoing endoscopic evaluation has led to real-time visualization of mucosal abnormalities and thus in vivo histology. The endomicroscopy (CLE) can improve IBD endoscopic evaluation by identifying seemingly normal-appearing mucosa, assessing the function of the intestinal barrier of the epithelium and vascular permeability, and by characterizing any mucosal lesions, including dysplastic lesions. CLE used during conventional endoscopy could especially facilitate the evaluation of mucosal healing in IBD. In addition, future developments in molecular imaging in IBD may optimize therapeutic approaches by identifying mucosal targets for therapy and determining the reasons for lack of response to specific therapy or subsequent loss of the response. |
| Databáze: | OpenAIRE |
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