Supplementary Data from Nanoparticle Encapsulation of Synergistic Immune Agonists Enables Systemic Codelivery to Tumor Sites and IFNβ-Driven Antitumor Immunity

Autor: Efstathios Karathanasis, Christopher J. Hoimes, Gil Covarrubias, Amy L. Goldberg, Michelle L. Wiese, Peter A. Bielecki, Carolyn Zheng, Taylor J. Moon, Vanitha Raguveer, Shruti P. Raghunathan, Prabhani U. Atukorale
Rok vydání: 2023
DOI: 10.1158/0008-5472.22421333
Popis: SF1: IFNβ production from macrophages by ELISA analysis; SF2: FMT imaging of mammary tumors ex vivo for spatial localization of nanoparticle; SF3: Confocal micrographs of DiI-nanoparticle fluorescence in mammary tumor tissue; SF4: Representative images of tumor masses 4 days post-treatment; SF5: Primary tumor bioluminescence and change in weight in 4T1 tumor-bearing mice; SF6: Confocal microscopy of a representative healthy lung section; SF7: Change in weight in B16F10 tumor-bearing mice
Databáze: OpenAIRE