Vitamin D and lactoferrin attenuate stress-induced colitis in Wistar rats via enhancing AMPK expression with inhibiting mTOR-STAT3 signaling and modulating autophagy

Autor:	Marian F. L. Abdelmalak, Dina S. Abdelrahim, Tari M. A. George Michael, Omnia M. Abdel‐Maksoud, Jolly M. W. Labib
Rok vydání:	2022
Předmět:	Clinical Biochemistry Cell Biology General Medicine Biochemistry
Zdroj:	Cell biochemistry and functionREFERENCES.
ISSN:	1099-0844
Popis:	Irritable bowel syndrome (IBS) is a global gastrointestinal disorder closely related to psychological stress exposure and local colonic inflammation. Herein, we investigated the effect of wrap-restraint stress (WRS) on rat behavior, on adenosine monophosphate-activated protein kinase-mammalian/mechanistic target of rapamycin-signal transducer and activator of transcription 3 (AMPK-mTOR-STAT3) signaling, and autophagy in colonic mucosa. The impact of chronic administration of vitamin D
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aabb34726cbab813941585cc324caf70 https://pubmed.ncbi.nlm.nih.gov/36588325 Zobrazit plný text záznamu Plný text