Effectiveness of 3% hypertonic saline nebulization in acute bronchiolitis among Indian children: A quasi-experimental study
| Autor: | Ruku Malik, Jay C Shah, Amitoz S Baidwan, Gurmeet Kaur, Vivek Vardhan Gupta, Pardeep P George, Neha Chitkara, Kushal Shinde, Krushnan V Bajaj, Harsh Vardhan Gupta |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment acute bronchiolitis lcsh:Medicine 03 medical and health sciences 3% hypertonic saline 0302 clinical medicine Quasi experimental study medicine Statistical analysis In patient 030212 general & internal medicine 0.9% saline with salbutamol Saline lcsh:R5-920 business.industry lcsh:R General Medicine Surgery Hypertonic saline 030228 respiratory system Acute Bronchiolitis Anesthesia Salbutamol Original Article Analysis of variance lcsh:Medicine (General) business 0.9% normal saline medicine.drug |
| Zdroj: | Perspectives in Clinical Research Perspectives in Clinical Research, Vol 7, Iss 2, Pp 88-93 (2016) |
| ISSN: | 2229-3485 |
| Popis: | Objective: To compare the effects of 3% hypertonic saline (HS) and 0.9% normal saline with nebulized 0.9% normal saline with salbutamol in patients of acute viral bronchiolitis. Materials and Methods: Participants were divided into three groups, that is, 3% HS group, 0.9% normal saline group and 0.9% saline with salbutamol group. Four doses at interval of 6 h were given daily until discharge. Average CS score and length of hospital stay were compared. One-way analysis of variance paired t-test and Chi-square test were utilized for statistical analysis. Results: The mean ages of the patients in three groups were 6.03 ± 3.71, 5.69 ± 3.34 and 5.48 ± 3.35 respectively. The 3rd day CS scores for all the groups were 1.0 ± 1.1, 1.9 ± 1.1 and 3.3 ± 0.5 respectively (P = 0.000). The average length of hospital stay was 3.4 ± 1.7, 3.7 ± 1.9 and 4.9 ± 1.4 days respectively (P = 0.001). Conclusion: The present study concludes that 3% HS nebulization (without additional bronchodilators) is an effective and safe treatment for nonasthmatic, moderately ill patients of acute bronchiolitis. The economic benefit of this comparably priced modality of treatment can be enormous in terms of hospital costs with parents returning to work sooner. |
| Databáze: | OpenAIRE |
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